AI RESEARCHarXiv9d ago

Altered Spatiotemporal Dynamics of Self-Referential Processing in Bipolar Disorder

Chen · P.-H. · Duncan · N. W. · Lee · H.-c. · Liu · Y.-J. · +2 more

Abstract

Background: Bipolar disorder is associated with persistent social, cognitive, and functional impairment during euthymia, yet the neural mechanisms underlying these deficits remain unclear. Alterations to self-referential processing are a candidate mechanism, but existing electrophysiological studies rely on emotionally valenced paradigms that potentially confound self-processing with emotional biases. Methods: We analysed electroencephalography from 28 patients with bipolar disorder (type I or I

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