9d ago
Evaluating Mean Platelet Volume in relation to Disease Severity in Paediatric Sickle Cell Anaemia: A Cross-Sectional Study in Kwara State, North-Central Nigeria
Oladimeji · F. D. · Adewoyin · A. D. · Oyeleke · K. O.
Abstract
Background: Sickle cell anaemia (SCA) is characterised by chronic haemolysis, inflammation, platelet activation, and recurrent vaso-occlusive complications. Mean platelet volume (MPV) is a readily available platelet index, but evidence regarding its relationship with disease severity in paediatric SCA remains limited and inconsistent, particularly in African populations. Objective: To evaluate the relationship between MPV and disease severity among children with SCA in Kwara State, North-Central
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