9d ago
Maternal cell-free RNA versus combined screening for first-trimester prediction of early-onset preeclampsia: a nested case-control study
Satorres-Perez · E. · Castillo-Marco · N. · Igual · M. · Cordero · T. · +12 more
Abstract
Background. In Europe, first-trimester combined screening with the Fetal Medicine Foundation (FMF) algorithm identifies women at increased risk of preeclampsia who may benefit from personalized aspirin prophylaxis. However, a substantial proportion of early-onset preeclampsia (EOPE) remains undetected at clinically acceptable specificity. Objective. To evaluate the first-trimester performance of MaiRa for early-onset preeclampsia (EOPE) risk stratification by benchmarking it against FMF screenin
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