9d ago
Non-Inferiority Margins in Randomized Controlled Trials in Abdominal Surgery- a Systematic Review
Leonhardt · C. · Birrer · D. · Stauffer · M. F. · Toti · J. M. A. · +8 more
Abstract
Importance Non-inferiority trials are becoming increasingly popular in abdominal surgery. The non- inferiority margin is critical in the interpretation and conclusion of these trials. Objective This systematic review aims to assess the methodological and reporting quality of non- inferiority randomized controlled trials in abdominal surgery. Evidence Review Non-inferiority trials were systematically identified by searching Ovid Medline, Embase and the CENTRAL databases from 2006 until December 2
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