AI RESEARCHarXiv9d ago

PHIHDL: A Novel HDL Index Predicting Baseline Pulmonary Hemodynamics and Long-Term Survival in PAH

Pritz · S. · Bordag · N. · Foris · V. · Biasin · V. · +22 more

Abstract

Rationale: Pulmonary hypertension is defined by pulmonary hemodynamics, but diagnostic and prognostic biomarkers remain limited. Nuclear magnetic resonance (NMR) spectroscopy provides detailed insights, particularly in the lipid metabolism. Objectives: To explore circulating NMR-derived metabolites and lipoprotein-related parameters for their association with pulmonary hemodynamics and to analyse their prognostic properties in pulmonary arterial hypertension (PAH). Methods: Retrospective analysi

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